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Manisha Balwani Selected Research

sphingosyl beta-glucoside

1/2022Plasma Glucosylsphingosine in GBA1 Mutation Carriers with and without Parkinson's Disease.
1/2022Reply to: No Evidence that Glucosylsphingosine Is a Biomarker for Parkinson Disease.
6/2021The role of glucosylsphingosine as an early indicator of disease progression in early symptomatic type 1 Gaucher disease.
1/2021Clinical outcomes after 4.5 years of eliglustat therapy for Gaucher disease type 1: Phase 3 ENGAGE trial final results.
11/2017Outcomes after 18 months of eliglustat therapy in treatment-naïve adults with Gaucher disease type 1: The phase 3 ENGAGE trial.
2/2016Recommendations for the use of eliglustat in the treatment of adults with Gaucher disease type 1 in the United States.

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Manisha Balwani Research Topics

Disease

18Gaucher Disease (Gaucher's Disease)
01/2022 - 09/2007
9Erythropoietic Protoporphyria
01/2021 - 01/2012
9Acute Intermittent Porphyria (Porphyria, Acute)
11/2020 - 08/2011
7Porphyrias (Porphyria)
09/2021 - 01/2012
6Wolman Disease (Wolman's Disease)
01/2022 - 11/2014
5Liver Diseases (Liver Disease)
01/2022 - 04/2013
4Dyslipidemias (Dyslipidemia)
01/2022 - 09/2013
4Parkinson Disease (Parkinson's Disease)
01/2022 - 06/2014
4Pain (Aches)
01/2022 - 07/2015
4Hepatic Porphyrias (Hepatic Porphyria)
10/2017 - 01/2012
3Fibrosis (Cirrhosis)
01/2022 - 09/2015
3Inborn Genetic Diseases (Disease, Hereditary)
09/2021 - 06/2011
3Body Weight (Weight, Body)
11/2020 - 09/2015
3Erythropoietic Porphyria (Congenital Erythropoietic Porphyria)
11/2019 - 01/2012
2Disease Progression
06/2021 - 01/2018
2Liver Failure
11/2019 - 01/2018
2Iron Overload
11/2012 - 01/2012
2Porphyria Cutanea Tarda
11/2012 - 01/2012
1Metabolic Bone Diseases (Osteopenia)
01/2021
1COVID-19
01/2021
1Down Syndrome (Down's Syndrome)
12/2020
1Injection Site Reaction
11/2020
1Cholelithiasis
01/2020
1Fatty Liver
01/2020
1Cholecystitis
01/2020
1Vascular Diseases (Vascular Disease)
01/2020
1Anemia
11/2019
1Fabry Disease (Fabry's Disease)
03/2018
1Chronic Pain
11/2016
1Lead Poisoning (Poisoning, Lead)
12/2015
1Myocardial Infarction
06/2015
1Psychotic Disorders (Schizoaffective Disorder)
06/2015
1Hyperplasia
06/2015
1Splenomegaly
02/2015
1Hypersensitivity (Allergy)
11/2014
1Edema (Dropsy)
11/2014
1Hepatomegaly
09/2013

Drug/Important Bio-Agent (IBA)

15Heme (Haem)IBA
09/2021 - 05/2010
10eliglustatIBA
01/2021 - 02/2015
9EnzymesIBA
01/2022 - 05/2010
7LipidsIBA
01/2022 - 11/2014
6Hemin (Panhematin)FDA Link
01/2022 - 08/2011
6Biomarkers (Surrogate Marker)IBA
01/2022 - 09/2007
6sphingosyl beta-glucosideIBA
01/2022 - 02/2016
5Acute Hepatic PorphyriaIBA
01/2022 - 02/2011
5Transaminases (Aminotransferases)IBA
11/2020 - 09/2013
4Sebelipase alfaIBA
01/2022 - 11/2014
4givosiranIBA
01/2022 - 01/2019
4PorphobilinogenIBA
01/2022 - 08/2011
4Glucosylceramides (Glucocerebrosides)IBA
06/2021 - 02/2016
4Hemoglobins (Hemoglobin)IBA
01/2021 - 02/2015
4AcidsIBA
01/2021 - 06/2011
3Glucosylceramidase (Glucocerebrosidase)IBA
01/2022 - 06/2014
3Aminolevulinic Acid (Levulan)FDA Link
01/2022 - 01/2019
3Ferrochelatase (Heme Synthetase)IBA
01/2021 - 04/2013
3GlucosidasesIBA
01/2021 - 06/2011
3protoporphyrin IXIBA
11/2019 - 04/2013
3imigluceraseFDA Link
09/2017 - 06/2015
35-Aminolevulinate SynthetaseIBA
04/2013 - 01/2012
2Cholesterol Esters (Cholesteryl Esters)IBA
01/2022 - 11/2014
2Triglycerides (Triacylglycerol)IBA
01/2022 - 11/2014
2PorphyrinsIBA
09/2021 - 12/2015
2chitotriosidaseIBA
01/2021 - 09/2007
2Sterol Esterase (Hormone-Sensitive Lipase)IBA
01/2020 - 09/2013
2Messenger RNA (mRNA)IBA
11/2019 - 01/2019
2Hydroxymethylbilane Synthase (Porphobilinogen Deaminase)IBA
01/2019 - 11/2016
2Carboxy-LyasesIBA
11/2012 - 01/2012
2DNA (Deoxyribonucleic Acid)IBA
11/2012 - 01/2012
1CholesterolIBA
01/2022
1Indicators and Reagents (Reagents)IBA
06/2021
1Nucleic AcidsIBA
01/2021
1CytokinesIBA
01/2021
1Piracetam (Nootropil)IBA
12/2020
1CreatinineIBA
11/2020
1Uroporphyrinogen III Synthetase (Uroporphyrinogen-III Synthase)IBA
11/2019
1Singlet OxygenIBA
11/2019
1Isoniazid (Ftivazide)FDA LinkGeneric
11/2019
1alpha-Galactosidase (Beano)IBA
03/2018
1Cytochrome P-450 CYP2D6 (CYP2D6)IBA
11/2017
1algluceraseFDA Link
09/2017
1ceramide glucosyltransferaseIBA
02/2016
1zinc protoporphyrinIBA
12/2015
1MetalsIBA
12/2015
1LDL CholesterolIBA
09/2015
1afamelanotideIBA
07/2015
1Melanocyte-Stimulating Hormones (MSH)IBA
07/2015
1hydroxymethylbilaneIBA
06/2015
1IronIBA
06/2015

Therapy/Procedure

15Therapeutics
09/2021 - 10/2009
7Enzyme Replacement Therapy
01/2018 - 11/2014
2Liver Transplantation
01/2018 - 06/2015
2Complementary Therapies (Alternative Medicine)
11/2016 - 10/2009
2Erythrocyte Transfusion
11/2012 - 01/2012
1Intravenous Administration
11/2020
1RNAi Therapeutics
11/2020
1Transplantation
11/2019
1Injections
01/2019
1Subcutaneous Injections
01/2019
1Splenectomy
01/2018
1Enzyme Therapy
01/2017